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Assessment of in vivo wound healing potentiality of Trapa natans L. leaves on different wound models in rat

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Title Assessment of in vivo wound healing potentiality of Trapa natans L. leaves on different wound models in rat
 
Creator Majee, Chandana
Mazumder, Rupa
Choudhary, Alka N
 
Subject Excision model
Hydroxyproline
Incision model
Trapa natans L.
 
Description 739-745
The primary goal of this study was to assess the wound healing potentiality of Trapa natans L. Excision and incision models were used to evaluate wound healing activity. For the excision model experiment was conducted for 21 days and for the incision model experiment continued for 10 days. Experimental animals were divided into four groups, the control group received simple ointment, the animal of the standard group treated with 0.2% w/w soframycin ointment, and the test groups received T. natans extract ointment (2.5% w/w & 5% w/w). Wound healing was determined by the rate of contraction, the time required for epithelization, collagen cell formation, the amount of hydroxyproline present in the wound site, and wound-breaking strength. Experimental results of the test showed a comparatively higher rate of contraction, lesser epithelization period, and higher hydroxyproline amount present in the wound area. These results were strengthened by the histopathological studies of the healing area tissues. When the standard and test groups were compared to the control group, statistically significant data were found (p
 
Date 2023-12-20T10:43:19Z
2023-12-20T10:43:19Z
2023-12
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/63049
https://doi.org/10.56042/ijtk.v22i4.7197
 
Language en
 
Relation Int Cl.23: A61K 36/00, A61K 36/185
 
Publisher NIScPR-CSIR,India
 
Source IJTK Vol.22(4) [October 2023]