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Effect of everolimus combined with anastrozole on serum FOXP 3 and MMP 9 in hormone receptor-positive elderly breast cancer patients

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Title Effect of everolimus combined with anastrozole on serum FOXP 3 and MMP 9 in hormone receptor-positive elderly breast cancer patients
 
Creator Hu, Shaofen
Li, Zhiling
Chen, Qin
 
Subject Estradiol
Hormone receptor positive
Luteinizing hormone
Objective response rate
Stomatitis
Tumor
 
Description 67-70
Breast cancer currently leads among all the types of cancer in
the total nmber of estimated cases worldwide, and holds fourth
position in total number of deaths caused by cancer. It calls for
early diagnosis and an effective treatment. Here, we explored the
effect of everolimus combined with anastrozole treatment on the
prognosis and serum FOXP 3 and matrix metalloproteinase 9
(MMP 9) in hormone receptor (HR) positive elderly breast cancer
patients. A total of 96 elderly patients with HR positive breast
cancer admitted to the hospital from April 2018 to April 2021
were selected and divided into two groups according to the
random number table method. The control group (n=48) was
given anastrozole, and the study group (n=48) was given
everolimus and anastrozole. Recent efficacy, estrogen, adverse
effects, survival rate, and test serum FOXP 3, MMP 9 levels were
recorded. The results showed higher objective response rate
(ORR) as (62.5%, 30/48) (41.67%, 20/48) (P
 
Date 2023-12-26T11:11:20Z
2023-12-26T11:11:20Z
2023-12
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/63084
https://doi.org/10.56042/ijeb.v62i01.7446
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJEB Vol.62(01) [Jan 2024]