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A short-term study on statistical numeration of multidrug resistant Escherichia coli isolates among the patients with urinary tract infection

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Title A short-term study on statistical numeration of multidrug resistant Escherichia coli isolates among the patients with urinary tract infection
 
Creator Srivastava, Neha
Verma, Sheetal
Singh, Meenu
Kumar, Abhinav
 
Subject Antibiotic resistance
Multiple antibiotic resistance index (MARI)
 
Description 119-125
Along with malaria and plague, urinary tract infections (UTIs) are among the oldest types of illnesses till today.
Antibiotics, however, have consistently been the initial treatment option chosen by medical specialists despite the fact that
treating this complex condition has never been simple. Antibiotic abuse or overuse is linked to the development of
resistance, the recurrence of illness, suffering, and financial hardship. In this study, we examed the pattern of Escherichia
coli antibiotic susceptibility in urine samples from UTI patients in a local population in India as well as the formation of
multiple drug resistances (MDR) among the isolates. The level of resistance to multiple antibiotics is accessed by multiple
antibiotic resistance index (MARI), a quantitative measure, which is determined by simply dividing number of antibiotics to
which the isolate is resistant to total number of antibiotics tested. We found that second and third generations of
flouroquinone were shown the highest levels of resistance, followed by widely used antibiotics like ampicillin and
cephalosporin. The drugs fosfomycin (FO) and nitrofurantoin (NIT) had the highest levels of sensitivity. In addition, we
observed 80% of isolates with multiple antibiotic resistance indexes more than 0.2 and 97% of isolates that are multidrug
resistant, which amply illustrates the severity of rising antibiotic resistance that must be properly controlled to treat UTI
effectively.
 
Date 2024-01-31T09:46:31Z
2024-01-31T09:46:31Z
2024-02
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/63275
https://doi.org/10.56042/ijeb.v62i02.2549
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.62(02) [Feb 2024]