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Therapeutic and prognostic studies in canine parvoviral gastroenteritis

Indian Agricultural Research Journals

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Title Therapeutic and prognostic studies in canine parvoviral gastroenteritis
 
Creator Kumar, Sanjeev
Sharma, Shukriti
D K, Gupta
A K, Sharma
V, Mahajan
 
Subject CPV, Immunochromatographic assay, Plasma therapy, Parvovirus
 
Description Canine parvoviral enteritis, a highly contagious and often fatal disease, is characterized by vomiting, foulsmelling haemorrhagic enteritis and severe dehydration. In this study conducted at multispecialty Veterinary Hospital of Guru Angad Dev Veterinary and Animal Sciences University (GADVASU), Ludhiana, 24 dogs confirmed with CPV Immuno-chromatographic assay(Ubio quick VET rapid Antigen test kit, Cochin, India) were divided into 3 treatment groups (8 dogs each) viz. conventional therapy (Group I), Conventionaland amino acid therapy (Group II) and conventional and plasma therapy (Group III). All these dogs were selected based on selection criteria of hypoproteinemia (total protein and albumin <4.5g/dL and ˂2.0g/dL, respectively). The levels of total protein increased in all the treatment groups within 7-days, however there was maximum rise in level of total protein from 3.9±0.11 to 5.93± 0.14 in group III followed by group II and least rise was seen in group I. Similar improvement was seen in albumin values in group III followed by group II and group I. Out of 24 dogs, 19 survived, while 5 pups died despite treatment. TLC, absolute neutrophils, absolute lymphocyte values were significantly lower in non-survivors as compared to survived dogs. Total protein and albumin levels were almost similar on day of first presentation between survivors and non-survivors groups. However subsequently, these levels increased markedly in survivor groups but showed no improvement in non-survivors’ group. The present study concludes that plasma therapy increases total protein and albumin levels in CPV affected pups; and these along with TLC, absolute neutrophils and absolute lymphocyte count can be used as prognostic indicators of CPV. 
 
Publisher Indian Society for Veterinary Medicine
 
Date 2024-02-11
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://epubs.icar.org.in/index.php/IJVM/article/view/148292
 
Source Indian Journal of Veterinary Medicine; Vol. 42 No. 2 (2022)
0970-051X
 
Language eng
 
Relation https://epubs.icar.org.in/index.php/IJVM/article/view/148292/53797
 
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