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Epidemiological, Hemato-biochemical and Therapeutic study on Nutritional Hemoglobinuria in Cattle and Buffaloes

Indian Agricultural Research Journals

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Title Epidemiological, Hemato-biochemical and Therapeutic study on Nutritional Hemoglobinuria in Cattle and Buffaloes
 
Creator Kataria, Chandan
A K, Sharma
D K, Gupta
 
Subject Nutritional hemoglobinuria, Urinalysis, Phosphorus, Sodium acid phosphate
 
Description A total of 22 animals (16 buffaloes and 6 cattle) suspected for nutritional hemoglobinuria were enrolled under the study. Blood and urine samples for various investigations were collected for hemato-biochemical and urine analysis. The results of epidemiological analysis revealed higher incidence of nutritional hemoglobinuria during winters as compared to other seasons. Most of the cases were recorded during postpartum period in both buffaloes and cattle. The highest incidence was seen in buffaloes and cattle in ≥ 5th lactation group (62.5% and 66.67%). Most of the cases (64.28% in buffaloes and 80% in cattle) were recorded within 0-30 days post-partum. Berseem constituted a major component (90%) of fodder for most nutritional hemoglobinuria affected animals. Brown red to coffee-coloured urine was the most obvious clinical symptom. The most predominantly observed clinical signs were reduced milk production (100%), followed by tenesmus (92.45%), coffee coloured urination (86.36%), pale mucous membrane (77.27%), completeanorexia (72.72%), constipation (68.18%), reduced water intake (45.45%) and other signs of gastro-intestinal disturbances. Heart rate and respiration rate were increased in both cattle and buffaloes. Significantly decreased (p<0.01) mean hemoglobin level, total erythrocyte count, packed cell volume, serum phosphorus and significantly increased (p<0.01) serum AST, total bilirubin, BUN, creatinine, glucose were recorded in hemoglobinuric cattle and buffaloes as compared to healthy controls. Total leukocyte count and absolute neutrophils count were significantly increased (p<0.05) in both cattle and buffaloes. No significant difference was recorded in absolute lymphocyte count, serum calcium and ALKP between affected and healthy animals. Urinalysis revealed presence of blood and leukocytes as common findings whereas microscopic examination revealed presence of epithelial cells, urothelial cells, few RBCs, and waxy casts. USG of kidney evidenced loss of parenchyma in most of the affected animals. After the treatment with sodium acid phosphate in combination with ascorbic acid, hemoglobin, PCV, total erythrocyte count and serum phosphorus improved significantly (p<0.01) and absolute neutrophils count decreased significantly (p<0.05) whereas, serum AST, total bilirubin, BUN, creatinine, and glucose decreased significantly (p<0.01). The recovery rate for combination therapy along with supportive treatment was found to be 59.09% respectively. 
 
Publisher Indian Society for Veterinary Medicine
 
Date 2024-02-11
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://epubs.icar.org.in/index.php/IJVM/article/view/148295
 
Source Indian Journal of Veterinary Medicine; Vol. 42 No. 2 (2022)
0970-051X
 
Language eng
 
Relation https://epubs.icar.org.in/index.php/IJVM/article/view/148295/53799
 
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