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Lorazepam Therapy for Canine Status Epilepticus

Indian Agricultural Research Journals

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Title Lorazepam Therapy for Canine Status Epilepticus
 
Creator R S, Parin
M, Ranjithkumar
A, Elamurugan
M, Chandrasekar
S, Kavitha
 
Description Canine status epilepticus is naturally occurring epilepsy in dogs, a life-threatening emergency needs to be treated immediately.  Prolonged episodes are known to cause damage in multiple areas of brain. For instantly stopping the seizure activity benzodiazepines are chosen as first-line therapy in dogs. The effectiveness of intravenous lorazepam has not yet been well established in veterinary patients. The purpose of the study was to find the seizure free interval in status epilepticus dogs when compared to diazepam. Twelve actively seizing dogs were randomly divided into two groups and administered with intravenous lorazepam @ 0.2mg.kg and diazepam @ 0.5 mg/kg. The parameters like physical parameters, seizure free period, level of consciousness and motor activity were analysed in both the groups. On evaluating the physical parameters there was a significant post ictal temperature when compare to control animals. There was a significant increase in seizure free period when compare to diazepam group. Lorazepam didn’t alter the level of consciousness and motor activity in treated dogs.    To conclude, lorazepam significantly increased the seizure free period when compared to diazepam in status epilepticus dogs.
 
Publisher Indian Society for Veterinary Medicine
 
Date 2024-02-22
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://epubs.icar.org.in/index.php/IJVM/article/view/147667
10.56093/IJVM.v43i2.147667
 
Source Indian Journal of Veterinary Medicine; Vol. 43 No. 2 (2023)
0970-051X
 
Language eng
 
Relation https://epubs.icar.org.in/index.php/IJVM/article/view/147667/53948
 
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