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Blue LED-driven C-N bond formation for synthesis of imidazopyridines
NOPR - NISCAIR Online Periodicals Repository
View Archive Info| Field | Value | |
| Title |
Blue LED-driven C-N bond formation for synthesis of imidazopyridines
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| Creator |
Jadhao, Amardeep R
Zyate, Shankesh C Gaikwad, Sanjay S |
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| Subject |
Blue LED irradiation (BLI)
C-N bond formation Transition metal-free IPs |
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| Description |
203-210
The formation of C-N bonds has emerged as a powerful key for structural modifications in organic synthesis. Although transition metal-free procedures provide a viable protocol to construct hetero molecules, the use of costly catalysts and high temperatures has restricted universal applicability. Moreover, radical-based C-N bond formation without the assistance of a transition metal catalyst has been a great challenge. Herein we report the blue LED-driven transition metal-free strategy for C-N bond formation. This reaction features easy-to-handle, mild reaction conditions, reactants and good functional group tolerance. The mechanistic investigation suggests that this strategy proceeds through phenacyl bromide radical precursor and NBS reaction mediated by H2O to construct IPs. |
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| Date |
2024-02-21T07:22:28Z
2024-02-21T07:22:28Z 2024-02 |
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| Type |
Article
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| Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/63371 https://doi.org/10.56042/ijc.v63i2.6338 |
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| Language |
en
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| Publisher |
NIScPR-CSIR,India
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| Source |
IJC Vol.63(02) [Feb 2024]
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