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Management of seasonal dermatitis in horses by using leaf extract of Aerva javanica

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Title Management of seasonal dermatitis in horses by using leaf extract of Aerva javanica
 
Creator Dedar, R K
Kumar, Naveen
Narnaware, Shirish D
Singh, Jitender
Legha, R A
Pal, Yash
 
Subject Aerva javanica
Alopecia
Dermatitis
Flavonoid
Horse
 
Description 154-161
Occurrence of seasonal allergic dermatitis, especially insect bite hypersensitivity and atopic dermatitis are very common
in horses. At present there is no satisfactory treatment is available for management of these skin allergies. Plant flavonoids
such as quercetin, kaempferol and their glycoside derivatives have been reported for their anti allergic and antiinflammatory
properties. In present study we have prepared an extract from the leaves of Aerva javanica, which was found
effective to manage clinical cases of seasonal allergic dermatitis in horses. Clinical signs of the allergic dermatitis in horses
were alopecia, thickening of skin and itching. On histopathological examination of skin biopsy samples taken from the
clinical cases epidermal hyperplasia, orthokeratotic and parakeratotic hyperkeratosis, spongiosis, occasional trichomalacia,
multifocal areas of aggregation of lymphocytes with or without infiltration of eosinophils were observed. Mass spectrometer
analysis of more purified extract suggested a glycoside of kaempferol may be an active ingredient of the extract.
 
Date 2024-02-22T11:15:23Z
2024-02-22T11:15:23Z
2024-02
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/63384
https://doi.org/10.56042/ijtk.v23i2.8723
 
Language en
 
Relation Int Cl.24: A61K 36/00
 
Publisher NIScPR-CSIR,India
 
Source IJTK Vol.23(2) [February 2024]