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Understanding the Role of NIR Laser Power and Wavelength in Tuning the Photothermal Transduction Efficiency of Gold Nanosystems in Biomedical Applications

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Title Understanding the Role of NIR Laser Power and Wavelength in Tuning the Photothermal Transduction Efficiency of Gold Nanosystems in Biomedical Applications
 
Creator Sankaranarayanan, Sri Amruthaa
Eswar, Kalyani
Balusu, Daideepkumar
Murugaiyan, Kavipriya
Ramakrishna, Bhuvanesh
Rengan, Aravind Kumar
 
Subject Photothermal transduction
Gold nanosystems
Photothermal agents
SPR
 
Description 87-92
Photothermal therapy (PTT) is an emerging, affordable alternative to conventional therapies for superficial tumors and
topical microbial infections. Photothermal agents (PTA) play a crucial role to achieve PTT. Several nanoparticles have been
widely used as PTA owing to their small size and tunability of absorbance in the near infrared region (NIR). When
irradiated with the NIR laser, they generate localized heat, which results in localized ablation of cancer cells or microbes.
Additionally, several organic or inorganic PTAs exhibit surface plasmon resonance (SPR), an important characteristic for
achieving laser-induced hyperthermia. However, among the various nano PTAs, the metallic nanosystems exhibit
comparatively better thermal raise properties. Among the metallic systems, gold is a superior, biocompatible, and wellstudied
system for PTT. However, the photothermal conversion efficacy of the PTAs greatly depend on the wavelength and
the power of the laser source used. In this regard, this study is aimed at understanding the photothermal conversion efficacy
of gold coated calcium peroxide nanoparticles when exposed to lasers of various wavelengths and power. The results
showed that the photothermal conversion efficacy (PTE) of the particles irradiated with continuos laser was higher, when
compared with the particles irradiated with low power pointer laser and pulsed laser.
 
Date 2024-02-26T09:28:23Z
2024-02-26T09:28:23Z
2024-02
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://nopr.niscpr.res.in/handle/123456789/63416
https://doi.org/10.56042/ijpap.v62i2.7420
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJPAP Vol.62(02) [February 2024]