Record Details

Conserved Orthology in Mitochondrial Genomes of Distantly Related Nematodes

DSpice at Indian Institute of Spices Research

View Archive Info
 
 
Field Value
 
Creator NIMA, P L
RIJU, A
REENA, N
EAPEN, S J
 
Date 2011-05-23T19:01:36Z
2011-05-23T19:01:36Z
2010
 
Identifier Proceedings of the International Symposium on Biocomputing, ACM Digital Library, http://doi.acm.org/10.1145/1722024.1722075.
http://hdl.handle.net/123456789/685
 
Description Identification of orthologous segments plays a very important role in comparative genomics studies. In the present study, we
have identified orthologous segments shared between Radopholus similis and 15 other nematodes. Complete genomes of 16 nematodes were used for the study. OSfinder
was used to find the orthologous segments shared between R.similis and other 15 nematodes. Orthologous segments were
visualized with the help of GTK powered Murasaki Visualizer (GMV) programme. Extremely AT rich genome of the
burrowing nematode R. similis, which has the largest mitochondrial genome, was found to have orthologous segments from start position, 4 to end position 16791 with 15
nematodes. Brugia malayi, Dirofilaria immitis, Onchocerca volvulus, and Xiphinema americanum share similar orthologous segment with that of R. similis. The mitochondrial
genome analysis revealed the presence of conserved gene locations in mitochondrion and the close evolutionary relationship of nematodes belonging to different clades and
different parasitic habitats. This study has many practical implications like reconstruction of ancestral genome of
nematode and calculation of evolutionary time.
 
Format 1093377 bytes
application/pdf
 
Language en
 
Subject Comparative genomics
Nematode
Synteny
Orthologous segments
Mitochondrial genome
 
Title Conserved Orthology in Mitochondrial Genomes of Distantly Related Nematodes
 
Type Article