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Antibacterial activity and biogenesis of silver and zinc nanoparticles by Streptomyces sp. strain ANB 1 isolated from marine water of Port Blair, India

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Title Antibacterial activity and biogenesis of silver and zinc nanoparticles by Streptomyces sp. strain ANB 1 isolated from marine water of Port Blair, India
 
Creator Hassan, N
Kumari, A
Saha, P
Rao, K V Bhaskara
 
Subject Actinomycetes
Antagonistic activity
Clinical pathogens
Multi-drug resistant pathogens
Nanoparticles
 
Description 189-197
The uncontrolled and random misuse of commercial antibiotics has led to the ever-increasing rise in drug resistant
bacteria. There is still a lag between the development of novel drugs and the emergence of drug resistant microorganisms.
Thus, multi-drug resistant microorganisms pose a serious threat to the human race. The marine environment has a great
biodiversity and is largely unexplored. It has proved to be an excellent source for isolating microorganisms that produce
secondary metabolites with unique properties. In the present study, the focus was to appraise the hostile behavior of marine
environment and isolate actinomycetes, which are capable of having antibacterial activity and also to synthesise metallic
nanoparticles. Biogenic metal nanoparticles bear immense potential as an alternative to conventional antibiotics. Out of 15
actinobacterial isolates, ANB 1 identified as Streptomyces sp. strain ANB 1 showed the most efficient antagonistic activity
against the clinical pathogens Klebsiella sp., Proteus sp., Escherichia coli, Pseudomonas sp. and Bacillus sp. The inhibition
zones varied in diameter from 5 – 20 mm. Further, Streptomyces sp. strain ANB 1 successfully synthesised silver and zinc
nanoparticles, which were characterised by the formation of characteristic peaks in the UV-Vis spectrophotometer. The
nanoparticles thus produced bear immense potential as an alternative to treat multi-drug resistant pathogens.
 
Date 2024-03-01T05:02:25Z
2024-03-01T05:02:25Z
2024-02
 
Type Article
 
Identifier 2582-6727 (Online); 2582-6506 (Print)
http://nopr.niscpr.res.in/handle/123456789/63502
https://doi.org/10.56042/ijms.v52i04.7658
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJMS Vol.52(04) [April 2023]