Record Details

Administration of Diethylcarbamazine Citrate to Rats-Redistribution of Lipids

DSpice at Indian Institute of Spices Research

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Field Value
 
Creator ZACHARIAH, JOHN T
KELEYSA RAJ, R
 
Date 2011-12-07T19:20:48Z
2011-12-07T19:20:48Z
1986
 
Identifier Journal of communicable diseases 18 (4): 302-305 (1986)
http://hdl.handle.net/123456789/764
 
Description Diethylcarbamazine citrate is the drug of choice in the treatment of flariasis. Administration of this drug in adult dose levels for a period of twelve days (300 mg/day for twelve days is one dose schedule recommended for the treatment of flariasis) brings about a change in the distribution of lipids in laboratory rats. The change is more marked in heart followed by brain, kidney and adipose. There was only marginal variation in the level of proteins. Carbohydrates were, however, unaffected. The study suggests that great care has to be taken while recommending long term use of DEC as a cure for flariasis, especially to people with any history of heart ailment.
 
Format 263021 bytes
application/pdf
 
Language en
 
Subject Diethylcarbamazine Citrate
Rats-Redistribution
Lipids
 
Title Administration of Diethylcarbamazine Citrate to Rats-Redistribution of Lipids
 
Type Article