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Evaluation of an in-house IgM/IgG lateral flow assay for serodiagnosis of human brucellosis

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Title Evaluation of an in-house IgM/IgG lateral flow assay for serodiagnosis of human brucellosis
Not Available
 
Creator Shome R
Patra S
Sahib MM
Shanmugam G
Dubey S
Skariah S
Shamshad S
Barman NN
Bora DP
Shome A
Nagalingam M
 
Subject ELISA
Human brucellosis
Lateral flow assay (LFA)
RBPT
SAT
 
Description Not Available
This study aimed to evaluate the diagnostic efficacy of an in-house lateral flow assay (LFA) for the detection of IgM/IgG anti-Brucella antibodies for rapid serodiagnosis of human brucellosis. Three groups of sera samples including 476 from high-risk individuals, 27 from culture-confirmed patients, and 43 from healthy blood donors were used for evaluation of LFA. In comparison with iELISA, the sensitivity, specificity, and accuracy of LFA were >95%, >99%, and 99% respectively. Considering the very good agreement, accuracy, simplicity, and rapidity, LFAs might be useful as a point of care test for the diagnosis of human brucellosis in resource-limited laboratories.
Not Available
 
Date 2024-03-06T15:28:45Z
2024-03-06T15:28:45Z
2023-02-03
 
Type Research Paper
 
Identifier Shome, R., Patra, S., Sahib, M.M., Shanmugam, G., Dubey, S., Skariah, S., Shamshad, S., Barman, N.N., Bora, D.P., Shome, A. and Mohandoss, N. (2023). Evaluation of an in-house IgM/IgG lateral flow assay for serodiagnosis of human brucellosis. Indian Journal of Medical Microbiology, 42: 55-58.
0973-7715
http://krishi.icar.gov.in/jspui/handle/123456789/81608
 
Language English
 
Relation Not Available;
 
Publisher Elsevier Publishers