Evaluation of an in-house IgM/IgG lateral flow assay for serodiagnosis of human brucellosis
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Title |
Evaluation of an in-house IgM/IgG lateral flow assay for serodiagnosis of human brucellosis
Not Available |
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Creator |
Shome R
Patra S Sahib MM Shanmugam G Dubey S Skariah S Shamshad S Barman NN Bora DP Shome A Nagalingam M |
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Subject |
ELISA
Human brucellosis Lateral flow assay (LFA) RBPT SAT |
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Description |
Not Available
This study aimed to evaluate the diagnostic efficacy of an in-house lateral flow assay (LFA) for the detection of IgM/IgG anti-Brucella antibodies for rapid serodiagnosis of human brucellosis. Three groups of sera samples including 476 from high-risk individuals, 27 from culture-confirmed patients, and 43 from healthy blood donors were used for evaluation of LFA. In comparison with iELISA, the sensitivity, specificity, and accuracy of LFA were >95%, >99%, and 99% respectively. Considering the very good agreement, accuracy, simplicity, and rapidity, LFAs might be useful as a point of care test for the diagnosis of human brucellosis in resource-limited laboratories. Not Available |
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Date |
2024-03-06T15:28:45Z
2024-03-06T15:28:45Z 2023-02-03 |
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Type |
Research Paper
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Identifier |
Shome, R., Patra, S., Sahib, M.M., Shanmugam, G., Dubey, S., Skariah, S., Shamshad, S., Barman, N.N., Bora, D.P., Shome, A. and Mohandoss, N. (2023). Evaluation of an in-house IgM/IgG lateral flow assay for serodiagnosis of human brucellosis. Indian Journal of Medical Microbiology, 42: 55-58.
0973-7715 http://krishi.icar.gov.in/jspui/handle/123456789/81608 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Elsevier Publishers
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