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ONECUT2 gene body methylation

Harvard Dataverse (Africa Rice Center, Bioversity International, CCAFS, CIAT, IFPRI, IRRI and WorldFish)

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Title ONECUT2 gene body methylation
 
Identifier https://doi.org/10.7910/DVN/UKER1G
 
Creator Li, Hong-Tao
 
Publisher Harvard Dataverse
 
Description The transcription factor ONECUT2 (OC2) serves as a master transcriptional regulator in metastatic castration-resistant prostate cancer (CRPC) and represents a potential therapeutic target. Despite its significance, the mechanism regulating OC2 remains unclear. This study aims to analyze the possible role of gene body methylation of OC2 in its expression regulation and as a biomarker and/or therapeutic target for aggressive prostate cancer (PCa)
 
Subject Medicine, Health and Life Sciences
ONECUT2, DNA methylation, prostate cancer
 
Date 2024-02-14
 
Contributor Li, Hong-Tao