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Synthesis, characterization and antimicrobial activity of Schiff base ligand and metal complexes

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Title Synthesis, characterization and antimicrobial activity of Schiff base ligand and metal complexes
 
Creator Rani, R Mamatha
Kavitha, P
 
Subject Quinoline Schiff base
Spectral properties
Antimicrobial activities
 
Description 281-285
This study describes the synthesis of a new Quinoline Schiff base by condensation of 3-formyl-2-hydroxyquinoline-5-
carbonitrile and 1-tosylhydrazine. After preparing Schiff base, metal complexes are formed using Cu(II), Ni(II), and Co(II).
FT-IR, 1H NMR, 13C NMR, ESI-MS, UV-Visible, XRD spectroscopy have all been able to demonstrate the full synthesis of
Schiff base and associated metal complexes. Preparations of compounds with low conductivity have been found to be nonelectrolytic.
The ligand has O, N, and O binding sites, according to the FT-IR data. According to the magnetic moment of
the compounds, the metal complexes of Cu(II), Ni(II), and Co(II) are paramagnetic. The compounds have been tested for
their properties against Bacillus subtilis, Escherichia coli, and Candida albicans. It has been found that metal (II) complexes
have potent antibacterial and antifungal action in comparison to ciprofloxacin and ketoconazole.
 
Date 2024-03-19T11:10:59Z
2024-03-19T11:10:59Z
2024-03
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/63593
https://doi.org/10.56042/ijc.v63i3.6539
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJC Vol.63(03) [March 2024]