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Embelin as an alternative reference standard for Delta-9-Tetrahydrocannibinol

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Title Embelin as an alternative reference standard for Delta-9-Tetrahydrocannibinol
 
Creator Pakrashy, Sourav
Majhi, Anjoy
Maurya, Pawan K
 
Subject Reference standard
Delta-9-Tetrahydrocannibinol
Embelin
Docking studies
Molecular mechanics
 
Description 390-393
Delta-9-Tetrahydrocannibinol (Δ9-THC), has shown neuroprotective effects on animal models, but cannot be used as a drug for
treatment as it is controversial to use an addiction drug for treatment. Further, there have been toxic and addictive effects on
humans. Embelin (isolated from Embelia ribes) falls under herbal medicine category. In this study it has been computationally
shown that the pharmacokinetic and drug-likeliness effects of Embelin are similar to Δ9-THC, and thus, it can be used as an
alternative reference standard as supported by docking studies.
 
Date 2024-04-16T09:08:57Z
2024-04-16T09:08:57Z
2024-04
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/63775
https://doi.org/10.56042/ijc.v63i4.7084
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.63(04) [April 2024]