Amphiphilic Copolymers having Saturated and Unsaturated Aliphatic Side Chains as Nano Carriers for Drug Delivery Applications
KRISHI: Publication and Data Inventory Repository
View Archive InfoField | Value | |
Title |
Amphiphilic Copolymers having Saturated and Unsaturated Aliphatic Side Chains as Nano Carriers for Drug Delivery Applications
Not Available |
|
Creator |
Bhavna Gupta,
Vijayendra Kumar, Gaurav Kumar, Abdullah Khan, Najam Akhtar Shakil, Ashish Dhawan, Virinder S. Parmar, Jayant Kumar Arthur C. Watterson |
|
Subject |
Nanocarriers, amphiphilic copolymers, encapsulation, drug delivery, bio-active, micelles and Novozyme-435
|
|
Description |
Not Available
Nano-particles with controllable particle size and shape are of great interest in biomedical applications (1). From the standpoint of drug carrier design with wide applicability to a variety of hydrophobic drugs, an effective strategy would be to prepare a simple copolymer having the property to form stable polymeric micelles which can entrap hydrophobic drugs in the core (2). In this study, we have attached saturated and unsaturated long chain acid chlorides to the copolymer of PEG and dimethyl-5-aminoisophthalate via an amide linkage in order to make the copolymers amphiphilic. Further, bioactive compounds like β-carotene, which has considerable double bond unsaturation and curcumin, which has considerable aromatic unsaturation, were encapsulated in these amphiphilic copolymers which successfully demonstrated their drug loading ability. Not Available |
|
Date |
2024-04-22T17:42:53Z
2024-04-22T17:42:53Z 2011-11-01 |
|
Type |
Research Paper
|
|
Identifier |
Bhavna Gupta, Vijayendra Kumar, Gaurav Kumar, Abdullah Khan, Najam A. Shakil, Ashish Dhawan, Virinder S. Parmar, Jayant Kumar & Arthur C. Watterson (2011): Amphiphilic Copolymers having Saturated and Unsaturated Aliphatic Side Chains as Nano Carriers for Drug Delivery Applications, Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 48:12, 1009-1015
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/82296 |
|
Language |
English
|
|
Relation |
Not Available;
|
|
Publisher |
Taylor and Francis
|
|