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Excellent Antimicrobial and Antibiofilm Effect of Herbal Extracts on Plaque Colonizers and Caries Inhabitants: An In-Vitro Study

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Title Excellent Antimicrobial and Antibiofilm Effect of Herbal Extracts on Plaque Colonizers and Caries Inhabitants: An In-Vitro Study
 
Creator Pathak, Anuja
Jain, Richa
 
Subject Biofilm
Broad-spectrum antimicrobial
Minimum Inhibitory Concentration
Traditional knowledge
Trifala
 
Description 511-516
Oral health and hygiene are of high concern with respect to human health. Most of the chemical formulation used to control
growth of unwanted oral microorganisms and biofilm formation causes several side effects in long term use. Traditional
knowledge and herbal extracts may offer better alternatives in addressing oral health issues. This study highlights inhibitory
effect of combination of Emblica officinalis, Terminalia belerica, Terminalia chebula (EOTBTC) and Linum usitatissimum
(LU) extracts on aerobic and anaerobic (facultative and strict) microorganisms and biofilms. EOTBTC and LU extracts were
found to inhibit the growth Streptococcus mutans, Candida albicans, Staphylococcus aureus, Lactobacillus acidophillus,
Fusobacterium nucleatum and Porphyromonas gingivalis. Zone of Inhibition (ZoI) ranged from 3 mm to 36 mm with EOTBTC
extract (6 to 36 mg/mL) and with LU extract (6 to 36 mg/mL), ZoI 5 mm to 23 mm. Minimum Inhibitory Concentration MIC of
all microorganisms reduced with EOTBTCLU, as compared to individual extract. Reduction in biofilm formation with
EOTBTCLU was also noticeable. C. albicans and S. aureus biofilms were more sensitive to extract (6 mg/mL) while
P. gingivalis have shown minimum reduction in biofilm at 24 mg/mL concentration. EOTBTCLU extract possessed broadspectrum
antimicrobial and antibiofilm effect and may prove to be better alternative for controlling microorganisms associated
with dental caries and biofilms.
 
Date 2024-05-06T11:15:53Z
2024-05-06T11:15:53Z
2024-05
 
Type Article
 
Identifier 0022-4456 (Print); 0975-1084 (Online)
http://nopr.niscpr.res.in/handle/123456789/63856
https://doi.org/10.56042/jsir.v83i5.4650
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source JSIR Vol.83(5) [May 2024]