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Co(II), Ni(II), and Cu(II) complexes with heterocyclic ligand and their biological applications

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Title Co(II), Ni(II), and Cu(II) complexes with heterocyclic ligand and their biological applications
 
Creator Rani, R Mamatha
Kavitha, P
 
Subject Analytical data
Schiff base
Antimicrobial activities
 
Description 452-456
In this work are described methods for generating and characterizing mononuclear, heterocyclic ligated Co(II), Ni(II), and Cu(II) and their complexes. The heterocyclic derivative Schiff base (E)-2-(4-bromobenzylideneamino)butanoic acid is produced by reacting 4-bromobenzaldehyde with 2-aminobutanoic acid. Experimental evidence has shown that the Schiff base forms four coordinated mononuclear complexes with the aforementioned metal ions at a 1:2 (metal:ligand) stoichiometry. FT-IR, UV-Vis, 1H and 13C NMR, and mass spectrometry are used to examine the structural modifications of the complexes. Additionally, the Schiff base and its complexes are evaluated for their antibacterial properties, and the findings are explained in detail. Antibacterial and antifungal activity of the metal (II) complexes have been shown to be very high and compared with ciprofloxacin andfluconazole.
 
Date 2024-05-20T04:50:27Z
2024-05-20T04:50:27Z
2024-05
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/63922
https://doi.org/10.56042/ijc.v63i5.8197
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJC Vol.63(05) [May 2024]