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<p>Effect of <em>Naga Parpam,</em> a metallic drug of Siddha<em> </em>medicine, on lipid peroxidation, antioxidant enzymes and tissues of liver in Wistar rats</p>

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Title Statement <p>Effect of <em>Naga Parpam,</em> a metallic drug of Siddha<em> </em>medicine, on lipid peroxidation, antioxidant enzymes and tissues of liver in Wistar rats</p>
 
Added Entry - Uncontrolled Name Ilango, Balakrishnan ; University of Colorado, Aurora.
Vinothkumar, Krishnamurthy ; VPro Bitech, Puducherry-605 110
Ezhilarasan, Devaraj ; Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (Deemed University)
Sukumar, Ethirajan ; VPro Bitech, Puducherry-605 110
 
Uncontrolled Index Term Naga Parpam, Wistar rats, Liver tissues, Lipid peroxidation, Antioxidant enzymes
 
Summary, etc. <em><span>Naga Parpam </span></em><span>(NP), a zinc containing drug is prescribed in Siddha medicine to treat </span><span>piles, fistula, dysentery, diarrhoea and tuberculosis</span><span>. In this investigation, NP’s effect on lipid peroxidation, antioxidant enzymes and tissues of liver in Wistar rats has been studied. The drug was administered orally in doses of 5, 10 and 20 mg/kg body weight for 28 days to the experimental animals. On day 29, they were sacrificed and the liver was removed. From the liver homogenate, lipid peroxidation (LPO) and the activities of antioxidant enzymes (catalase, superoxide dismutase and glutathione peroxidase) were analyzed. Dose dependent decrease in LPO and increase in the above enzymes revealed its potential antioxidant activity. There were no significant changes in the tissue architecture in histology that further confirmed the pro-active role of NP in treating diseases.</span>
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2024-05-27 15:19:02
 
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http://op.niscair.res.in/index.php/IJTK/article/view/60147
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 23, ##issue.no## 5 (2024): Indian Journal of Traditional Knowledge
 
Language Note en