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Ultrasound assisted synthesis, molecular docking and antimicrobial activities of some aryl sulfonamides

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Title Ultrasound assisted synthesis, molecular docking and antimicrobial activities of some aryl sulfonamides
 
Creator Nalini, S
Divya, J
Gayathri, P
Muthuvel, I
Thirunarayanan, G
Manikandan, V
Usha, V
 
Subject Aryl sulfonamides
Ultrasound assisted synthesis
Ferric chloride-bentonite
Molecular docking
Antimicrobial activities
 
Description 557-571
A series of aryl sulfonamides have been synthesised with more than 70% yield using ultrasound assisted condensation of aryl sulfonyl chloride and aryl amines in the presence of ferric chloride-bentonite in ethanol medium. The synthesised sulfonamides have been characterized from their physical constants, infrared and NMR spectroscopic data. In this synthetic method, the effect of catalyst and solvents on the yields have been studied. The molecular docking analysis of these sulfonamides have been investigated by finding protein-ligand interaction and binding affinities. Antimicrobial activities of these sulfonamides have been studied against selected microbes.
 
Date 2024-06-21T11:55:12Z
2024-06-21T11:55:12Z
2024-06
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/64078
https://doi.org/10.56042/ijc.v63i6.8837
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC Vol.63(06) [June 2024]