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In Vivo evaluation of wound healing efficacy of κ -Carrageenan blended polyvinyl pyrrolidinone films for wound dressing applications

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Title In Vivo evaluation of wound healing efficacy of κ -Carrageenan blended polyvinyl pyrrolidinone films for wound dressing applications
Not Available
 
Creator Amruth, P.
Rosemol Jacob, M.
Joy, J. M.
Anandan, R.
Suseela Mathew
 
Subject Seaweed
Carrageenan dressing film
Wound closure
Wound healing
 
Description Not Available
The requisite for novel potential dressings has emerged as a consequence of the incidences of injuries caused due to second
intention and expensive treatment costs for the management of them. New generation dressings are capable to accelerate
proliferation of cells and regeneration of tissue despite of the protective role to the wounds. Moreover, patient compliance
persists as an integral factor with regard to the fact that they create no damage to the newly regenerated tissue on removal
of the same. In the current study, we developed a κ- carrageenan film dressing, which is capable to accelerate tissue repair
and aids its removal by external stimulus without disturbing the regenerated tissue. The dressing is capable to absorb
excessexudate from the wound by maintaining hydrationto wound bed. The medical dressing was evaluated in male Wistar
rats by generating a pocket wound. The dressings were implanted in incised pocket wound for 16 days. Histological
analyses demonstrated that the dressing inserted on the injured area have showed minimal level of inflammatory events and
generated denser connective tissue on comparison to wounds devoid of dressings. The injured site sheltered with the
dressing demonstrated re-epithelization and angiogenesis to promote wound closure.
Not Available
 
Date 2024-06-07T18:27:02Z
2024-06-07T18:27:02Z
2023-08-31
 
Type Research Paper
 
Identifier Amruth, P., Rosemol Jacob, M., Joy, J. M., Anandan, R. and Suseela Mathew (2023) In Vivo evaluation of wound healing efficacy of κ -Carrageenan blended polyvinyl pyrrolidinone films for wound dressing applications. International Journal of Zoology and Applied Biosciences. 8(4):16-20.
2455-9571
http://krishi.icar.gov.in/jspui/handle/123456789/83348
 
Language English
 
Relation Not Available;
 
Publisher Rishan Publications