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Evolution, Characteristics, and Clonal Expansion of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA): Global Perspectives

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Title Evolution, Characteristics, and Clonal Expansion of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA): Global Perspectives
Not Available
 
Creator Muneeb Hamza
Sivaraman, G. K.
Prasad, M. M.
 
Subject MRSA
LA-MRSA
Zoonosis
Livestock
Clonal complex
CC398
 
Description Not Available
Epidemiological classification of methicillin-resistant Staphylococcus aureus (MRSA) as hospital-associated MRSA (HA-MRSA), community-associated MRSA (CA-MRSA), and livestock-associated MRSA (LA-MRSA) has become more complex and unclear. Nevertheless, the global burden of LA-MRSA and its clinical complications have been increased to unprecedented levels. The improper use of antibiotics contributed to the emergence of MRSA in the livestock sector. Apart from infections, asymptomatic colonization of MRSA in humans and animals can result in the humanosis and/or zoonosis. The LA-MRSA studies drew attention because of its unique properties of harboring the mecC locus (an analogue of mecA) as the methicillin resistance determinant and varying staphylococcal cassette chromosome mec (SCCmec) elements. The peculiar feature of LA-MRSA which is non-typeable by SmaI-pulsed-field gel electrophoresis (SmaI-PFGE) has opened different vistas in LA-MRSA research. The present chapter focused on the prevalence, history of evolution, clonal expansion, and epidemiological characteristics of LA-MRSA from global perspectives. Concerted efforts were made to encompass the major aspects of LA-MRSA by analyzing the related studies. Over the years, LA-MRSA gained special attention owing to its widespread and zoonotic potential.
Not Available
 
Date 2024-06-07T12:58:16Z
2024-06-07T12:58:16Z
2023-03-24
 
Type Book chapter
 
Identifier Muneeb Hamza, Sivaraman, G. K. and Prasad, M. M. (2023) Evolution, Characteristics, and Clonal Expansion of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA): Global Perspectives. In: Prasad, M. M., Ravishankar, C. N., Murugadas, V., Rajesh Bhatia, Joykrushna Jena and Madhusudana Rao, B. (eds) (2023) Handbook on Antimicrobial Resistance. Springer Singapore. Pp 1-20.
978-981-16-9723-4
http://krishi.icar.gov.in/jspui/handle/123456789/83176
 
Language English
 
Relation Not Available;
 
Publisher Springer