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Metabolomics‐Based Mechanistic Insights into Revealing the Adverse Effects of Pesticides on Plants: An Interactive Review

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Title Metabolomics‐Based Mechanistic Insights into Revealing the Adverse Effects of Pesticides on Plants: An Interactive Review
Not Available
 
Creator Mohammad Shahid 1,*, Udai B. Singh 1 and Mohammad Saghir Khan 2
 
Subject pesticides; toxicological consequences; metabolomic analysis; metabolic pathways
 
Description Not Available
: In plant biology, metabolomics is often used to quantitatively assess small molecules,
metabolites, and their intermediates in plants. Metabolomics has frequently been applied to detect
metabolic alterations in plants exposed to various biotic and abiotic stresses, including pesticides.
The widespread use of pesticides and agrochemicals in intensive crop production systems is a
serious threat to the functionality and sustainability of agroecosystems. Pesticide accumulation in
soil may disrupt soil–plant relationships, thereby posing a pollution risk to agricultural output.
Application of metabolomic techniques in the assessment of the biological consequences of
pesticides at the molecular level has emerged as a crucial technique in exposome investigations.
State‐of‐the‐art metabolomic approaches such as GC–MS, LC–MS/MS UHPLC, UPLC–IMS–QToF,
GC/EI/MS, MALDI‐TOF MS, and 1H‐HR‐MAS NMR, etc., investigating the harmful effects of
agricultural pesticides have been reviewed. This updated review seeks to outline the key uses of
metabolomics related to the evaluation of the toxicological impacts of pesticides on agronomically
important crops in exposome assays as well as bench‐scale studies. Overall, this review describes
the potential uses of metabolomics as a method for evaluating the safety of agricultural chemicals
for regulatory applications. Additionally, the most recent developments in metabolomic tools
applied to pesticide toxicology and also the difficulties in utilizing this approach are discussed.
Not Available
 
Date 2024-06-24T16:44:30Z
2024-06-24T16:44:30Z
2023-01-01
 
Type Research Paper
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/83754
 
Language English
 
Relation Not Available;
 
Publisher Not Available