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Water extract of pomegranate ash (WEPA) catalyzed, green and efficient, one-pot multicomponent synthesis of 5-aminopyrazole-4-carbonitrile

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Title Water extract of pomegranate ash (WEPA) catalyzed, green and efficient, one-pot multicomponent synthesis of 5-aminopyrazole-4-carbonitrile
 
Creator Patil, Kiran N
Ingale, Vivek S
Dafale, Pankaj S
Patil, Rushikesh M
Patil, Annappa I
Patil, Pravin D
 
Subject Pyrazole
WEPA (Water extract of pomegranate ash)
Green organic solvent
Knoevenagel condensation
Green chemistry
 
Description 709-715
In this work, we have described one pot multicomponent synthetic approach for 5-aminopyrazole-4-carbonitrile synthesis
by using WEPA (Water Extract of Pomegranate Ash) as an organo catalyst. A series of substituted derivatives of product
have been synthesized using this easy and efficient catalyst as a green organic solvent. The reaction involves condensation
of malononitrile, benzaldehyde and phenylhydrazine generating one-pot pyrazole product. The synthetic route of this work
involves green solvent and less hazardous reactions. The advantages of this protocol are short reaction periods, high yield of
products, safe and easy procedures and operational simplicity.
 
Date 2024-07-19T07:02:06Z
2024-07-19T07:02:06Z
2024-07
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/64258
https://doi.org/10.56042/ijc.v63i7.7749
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJC Vol.63(07) [July 2024]