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IN VITRO ANTIMICROBIAL EFFECT OF OXYCLOZANIDE ANTHELMINTIC AGAINST DRUG RESISTANT STAPHYLOCOCCUS AUREUS ISOLATED FROM BOVINE MASTITIS MILK

Indian Agricultural Research Journals

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Title IN VITRO ANTIMICROBIAL EFFECT OF OXYCLOZANIDE ANTHELMINTIC AGAINST DRUG RESISTANT STAPHYLOCOCCUS AUREUS ISOLATED FROM BOVINE MASTITIS MILK
 
Creator A. Elamaran
P. Senthil Kumar
V. Ranganathan
K. Kannan
T. Ramasamy
C.M. Jaikanth
S. Senthil Kumar
J. Vijay Anand
 
Subject Bovine Mastitis
Oxyclozaninde
MRSA
In vitro
MIC
 
Description This study investigated oxyclozanide, a salicylanilide anthelmintic, as an alternative treatment for Methicillin-resistant Staphylococcus aureus (MRSA) in bovine mastitis. With conventional treatments facing challenges due to antibiotic resistance, oxyclozanide demonstrated promising in vitro antimicrobial effect against MRSA isolates. The minimal inhibitory concentration (MIC) ranged from 0.5 to 1.0 μg/ml, indicating its efficacy. Oxyclozanide’s mechanism involved disrupting the transmembrane structure of bacteria, presenting a potential strategy against MRSA. This suggested the repurposing of oxyclozanide as a viable option for combating MRSA in bovine mastitis, prompting further investigation into its precise mechanism and therapeutic potential. 
 
Publisher Tamil Nadu Veterinary and Animal Sciences University
 
Date 2024-08-16
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://epubs.icar.org.in/index.php/IJVASR/article/view/154849
10.56093/ijvasr.v53i3.154849
 
Source Indian Journal of Veterinary and Animal Sciences Research; Vol. 53 No. 3 (2024): IJVASR May - June 2024; 12-20
2347-2774
 
Language eng
 
Relation https://epubs.icar.org.in/index.php/IJVASR/article/view/154849/55428
 
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