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Assessment of growth inhibitory activity of Withania somnifera L., Indian Ginseng against Escherichia coli

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Title Assessment of growth inhibitory activity of Withania somnifera L., Indian Ginseng against Escherichia coli
 
Creator Joshi, Vaishnavi
Chaudhary, Ashu
Shazad, Mohd
Singh, Aviral
Kayesth, Sunil
 
Subject Escherichia coli
Growth inhibitory
Withania somnifera
Ws-REE
 
Description 330-333
The current investigation is focused on the antibacterial potential
of Withania somnifera Dunal roots. Ashwagandha root powder
contains many bioactive components like alkaloids, tannins,
flavonoids, and phenolic compounds. These substances have a variety
of recognised medicinal, antimicrobial, and antibacterial properties.
This study has investigated the antibacterial activity of W. somnifera
root ethanol extract (Ws-REE). Three concentrations, 0.5, 1, and 2%,
were employed for the treatment. The concentration of E. Coli cell
culture was determined by using a spectrophotometer. The control
group exhibited the highest measured cell density of 1.3 X 109
cells/mL. In the measured concentration, the dose-dependent impact
was noted. For 0.5, 1, and 2% of the sample, the bacterial cell density
was 4.24 X 108, 1.2 X 108, and 8.0 X 106, respectively. The growth
inhibitory activities of W. somnifera extract against E. coli may be due
to specific chemical compounds or synergistic effects of the
compounds present in the extract.
 
Date 2024-08-06T05:06:58Z
2024-08-06T05:06:58Z
2024-08
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscpr.res.in/handle/123456789/64366
https://doi.org/10.56042/ijnpr.v15i2.11663
 
Language en
 
Relation Int. cl. (2021.01)− A61K 36/00, A61K 36/81, A61K 125/00, A61P 31/00, A61P 31/04
 
Publisher NIScPR-CSIR,India
 
Source IJNPR Vol.15(2) [June 2024]