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Ascertaining antibacterial potential of Cassia fistula against Escherichia coli

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Title Ascertaining antibacterial potential of Cassia fistula against Escherichia coli
 
Creator Kumari, Dipshikha
Saini, Priyanka
Singh, Aviral
Shazad, Mohd
 
Subject Antibacterial activity
Cassia fistula
Escherichia coli
 
Description 325-329
The emergence of antibiotic resistance has forced scientists to
use natural products to fight against microbes. Cassia fistula L.
has been used in traditional medicine to treat various diseases
such as diarrhoea, skin diseases, fever, abdominal pain, leprosy,
etc. The present study focussed on the growth inhibitory activity
of C. fistula leaf ethanol extract against Escherichia coli DH5α
strain. The antibacterial activity of three different concentrations
(2, 1, and 0.5%) of C. fistula leaf extract was investigated. The
results showed that the extract inhibited the growth of E. coli
significantly. The density of E. coli in the control group was
1.97×109 cells/mL. The number of cells in the treatment at 2%
extract concentration was significantly reduced; after 24 hours,
1.04×108 cells/mL were detected. In the treatments at 1% and
0.5% concentrations, there were noticeably fewer cells than in the
control (6.48 x 108 and 7.04 × 108 cells/mL, respectively). It was
found that the extracts' antibacterial effectiveness varied in a dosedependent
manner. Several secondary metabolites were present in
C. fistula, which contributed to its antibacterial action.
 
Date 2024-08-06T05:08:51Z
2024-08-06T05:08:51Z
2024-08
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscpr.res.in/handle/123456789/64367
https://doi.org/10.56042/ijnpr.v15i2.11664
 
Language en
 
Relation Int. cl. (2021.01)− A61K 36/00, A61K 36/48, A61K 127/00, A61P 31/00, A61P 31/04
 
Publisher NIScPR-CSIR,India
 
Source IJNPR Vol.15(2) [June 2024]