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Investigation of Acacia nilotica seed gum for formulation prospects

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Title Investigation of Acacia nilotica seed gum for formulation prospects
 
Creator Kumar, Geetendra
Singh, Narendra Kumar
Srivastava, Manjoosha
 
Subject A. nilotica
Characterization
Excipient
Gum
Seed
 
Description 780-786
Plant gums are useful excipient materials for preparation of different health care formulations. Gums are generally
carbohydrates, which consist of long chain polysaccharides. Traditionally, plant gums have been utilized for preparation of
different drug delivery systems. A. nilotica seed has nutritional and ethnobotanical values, which has been traditionally used
as food and folk medicine. Thus, the purpose of this study was separation of A. nilotica seed endosperm and isolation of
endospermic gum for exploration of their physicochemical properties. Result revealed that isolated endospermic gum was
amorphous in nature based on SEM and XRD analysis. Elements C, K and Mg were found to be attached on gum surface in
EDS analysis pH, tapped and true density were found to be closer in seed endosperm and their isolated gum.
Hygroscopicity, water holding capacity, porability, swelling index, angle of repose and porosity were enhanced in isolated
gum. Tensile strength and viscosity of isolated gum i.e., 60.93 mN.m-1 and 5-200 cP respectively, were increased as
compared to seed endosperm i.e., 55.73 mN.m-1 and 4-100 cP respectively. Thus, isolated endospermic gum was found to be
suitable in terms of physicochemical properties and may be used as plant based safe, non-toxic and eco-friendly excipient
material in pharmaceutical applications.
 
Date 2024-08-22T06:46:35Z
2024-08-22T06:46:35Z
2024-08
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/64433
https://doi.org/10.56042/ijtk.v23i8.3492
 
Language en
 
Relation Int Cl.24: A23L 29/25, A61K 9/34
 
Publisher NIScPR-CSIR,India
 
Source IJTK Vol.23(8) [August 2024]