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Antimicrobial and antioxidant properties of peel and seed extract of Carica papaya L.

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Title Antimicrobial and antioxidant properties of peel and seed extract of Carica papaya L.
 
Creator Vasundra
Dutta, Upma
 
Subject Antimicrobial
Antioxidant
Functional foods
Nutraceutical
Papaya waste
 
Description 660-669
Carica papaya is a widely consumed fruit in many tropical areas of the world, but its peel and seeds are generally
discarded as waste material. However, peels and seeds consist of various natural bioactive compounds that are responsible
for many medicinal and therapeutic properties and can be further used in various industries for functional foods,
pharmaceuticals, and cosmetic products. Since ancient times, the entire plant of Carica papaya L., including the peel, seeds,
leaves, etc., has been used as traditional medicine. Here, we studied the phytochemical constituents, antimicrobial and
antioxidant activities of papaya waste (peel and seeds) samples obtained from the local market in Jammu district of Jammu
& Kashmir. Antimicrobial assessment using the agar-well diffusion method revealed the substantial efficacy of both the
extracts. At a concentration of 100 μg/mL, both papaya peel and seed ethanolic extracts exhibited substantial zones of
inhibition against Escherichia coli (16.00±1.00 mm and 19.40±1.15 mm), Bacillus cereus (21.50±1.00 mm and 08.00±1.00
mm), Klebsiella pneumoniae (25.50±1.00 mm and 20.00±1.00 mm) and Staphylococcus aureus (14.40±1.15 mm and
7.50±1.00 mm), respectively. The minimum inhibitory concentration (MIC) was determined using the macro broth dilution
method, indicating that the seed extract had a maximum MIC of 100 μg/mL against all test pathogens, surpassing the peel
extract. The qualitative analysis showed that phytochemicals including tannins, saponins, alkaloids and phytosteroids were
absent in both the extracts. The bioactive potential of papaya peel and seeds is quantified by determining their total phenol
content and total flavonoid content. The papaya seeds exhibited TPC of 62.45 mg GAE’s/gdw and a TFC of 47.84 mg
QE’s/gdw, followed by papaya seeds. The peel extract demonstrated significant antioxidant potential, exhibiting remarkable
DPPH radical scavenging activity (IC50 value: 55.50 μg/mL) and β-carotene/linoleic acid assay (IC50 value: 75.80 μg/mL),
surpassing the seed extract. This study concludes that papaya waste can be a good source of antimicrobial and antioxidant
agents.
 
Date 2024-09-09T05:59:32Z
2024-09-09T05:59:32Z
2024-09
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/64485
https://doi.org/10.56042/ijeb.v62i08.5178
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJEB Vol.62(08) [August 2024]