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Antibiofilm, antiquorum sensing and antioxidant activities of Calendula officinalis L., Hypericum perforatum L. and Trachystemon orientalis (L.) G. Don essential oils

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Title Antibiofilm, antiquorum sensing and antioxidant activities of Calendula officinalis L., Hypericum perforatum L. and Trachystemon orientalis (L.) G. Don essential oils
 
Creator Gedik, B
Akkoyunlu, A
Dulger, G
 
Subject Biofilm
Chromobacterium violaceum ATCC 12472
Oxidative stress index
 
Description 654-659
Bacteria can coordinate biofilm formation through antiquorum sensing and create a more effective defense mechanism.
Therefore, strategies that inhibit biofilm formation and target the antiquorum sensing mechanism are needed to combat
antibiotic resistance. This study was conducted to determine the antibiofilm and antiquorum sensing (anti-QS) effect of essential
oils (EOs) obtained from Calendula officinalis L., Hypericum perforatum L. and Trachystemon orientalis (L.) G. Don. and also
to calculate oxidative stress indices (OSI) by analysing oxidant and antioxidant capacity. Antibiofilm capacities of EOs against
Escherichia coli were investigated by microplate method. Anti-QS activities were evaluated with the agar well diffusion test.
The oxidant capacities of plant EOs, whose antioxidant value was determined with the Total Antioxidant Status kit (TAS), were
also examined with the Total Oxidant Status kit (TOS), and the OSI were calculated from the ratio of the two. EOs of all three
plants have strong antibiofilm and anti-QS effects. T. orientalis, which has 19 mm+ anti-QS effect, shows 93.11% biofilm
inhibition effect and draws attention together with the other two plants used pharmacologically. EOs with low OSI levels are
expected to have high phytotherapeutic efficacy. As expected, the EOs used are considered important components for their
capacity to inhibit biofilm formation and the QS mechanism. This study constitutes the first step in using EOs as alternative
agents for strategies that prevent the anti-QS mechanism and biofilm formation.
 
Date 2024-09-09T06:11:41Z
2024-09-09T06:11:41Z
2024-09
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscpr.res.in/handle/123456789/64486
https://doi.org/10.56042/ijeb.v62i08.5943
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJEB Vol.62(08) [August 2024]