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The effect of different doses of Tarantula-Logoplex® on oxidative status and biochemical parameters in Japanese quails

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Title The effect of different doses of Tarantula-Logoplex® on oxidative status and biochemical parameters in Japanese quails
 
Creator Tufan, Oznur
Arslan, Mustafa Sedat
Uslu, Muhittin
Er, Ayse
 
Subject Biochemical
Logoplex
Oxidative stress
Quail
 
Description 869-872
Two commercial forms of Tarantula cubensis (TC) extract are used as homeopathic agents in veterinary medicine. These are Tarantula-Logoplex® (TL) and Theranekron® (THR). This study aims to evaluate the effect of TL on albumin (ALB), aspartate aminotransferase (AST), alkaline phosphatase (ALP), cholesterol (CHO), creatinine (CRE), blood urea nitrogen (BUN), malondialdehyde (MDA), superoxide dismutase (SOD) and catalase (CAT) values in healthy quails. A total of 24 Japanese quails were divided into 2 equal groups TL0.6 (n: 12, 0.6 mL/animal, IM) and TL0.8 (n: 12, 0.8 mL/animal, IM). Before the application, control blood was taken from the medial metatarsal vein of 6 quails in each group. Blood was drawn from the medial metatarsal vein at the 2nd, 4th, 8th, 24th and 48th hours after administration (6 quails were used at each sampling time). Animals were euthanized by decapitation after blood collection at the last sampling time. ALB, AST, ALP, CHO, CRE and BUN levels were measured with an auto-analyzer, whereas MDA, SOD and CAT values were determined with an ELISA reader. TL caused increases in hepatic damage markers (AST, ALP) and fluctuations in oxidative stress markers (MDA, SOD). Due to the increase in AST and ALP values in Japanese quail, it is recommended to be careful when using TL at these doses.
 
Date 2024-09-23T09:30:51Z
2024-09-23T09:30:51Z
2024-09
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/64565
https://doi.org/10.56042/ijtk.v23i9.13617
 
Language en
 
Relation Int Cl.24: A61K 9/00, A61K 36/00
 
Publisher NIScPR-CSIR,India
 
Source IJTK Vol.23(9) [September 2024]