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Activity of the Hura crepitans (Linn.) seeds as gastrointestinal antiparasitic in fattening lambs

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Title Activity of the Hura crepitans (Linn.) seeds as gastrointestinal antiparasitic in fattening lambs
 
Creator Escalera-Valente, Francisco
Gutiérrez-Leyvaa, Ranferi
Loya-Olguín, José Lenin
Carmona-Gasca, Carlos Alfredo
Martínez-González, Sergio
Loeza-Concha, Henry Jesús
González-Montaña, Jose Ramiro
 
Subject Blood
Hura crepitans
Natural antiparasitic
Phytotoxicity
Sheep
Vital signs
 
Description 853-861
The seed latex of Hura crepitans (Linn.) has been used for managing various diseases in both humans and animals, including as an intestinal antiparasitic against nematodes and coccidia in sheep. This research aimed to evaluate the antiparasitic efficacy of H. crepitans seeds, determine the effective dose for this effect, and assess any potential toxic effects on fattening lambs and their impact on blood parameters. Six ewe lambs were administered different doses of H. crepitans seeds (ranging from 0.16 to 6 g/kg b. w.). The antiparasitic efficacy was assessed by measuring the presence of gastrointestinal parasites, oocysts per gram of feces (opg), and eggs per gram of feces (epg). No significant changes were observed in feed intake or body weight. Vital signs, blood parameters, and most biochemical variables evaluated (AP, GGT, and TP) remained stable, with no increases in AST, ALT, or LDH even at the highest doses (4 and 6 g/kg b. W.). The absence of significant adverse effects or alterations in the measured blood variables suggests that Hura crepitans seeds can be administered to lambs as a gastrointestinal antiparasitic at doses up to 6 g/kg b. w. without causing side effects.
 
Date 2024-09-23T09:35:30Z
2024-09-23T09:35:30Z
2024-09
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/64567
https://doi.org/10.56042/ijtk.v23i9.1539
 
Language en
 
Relation Int Cl.24: A61K 36/00
 
Publisher NIScPR-CSIR,India
 
Source IJTK Vol.23(9) [September 2024]