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Cu(II) complexes with heterocyclic Schiff bases of 2-amino benzoxazole and acetophenone derivatives: Synthesis, characterization and biological activity

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Title Cu(II) complexes with heterocyclic Schiff bases of 2-amino benzoxazole and acetophenone derivatives: Synthesis, characterization and biological activity
 
Creator Kumari, Suman
Seema
Yadav, Poonam
Sharma, Shobhana
Ranka, Mamta
 
Subject 2-Aminobenzoxazole
Heterocyclic Schiff bases
Metal complexes
Antifungal potential
Antibacterial potential
 
Description 914-922
Two heterocyclic Schiff bases (named- CO, HO) have been developed from 2-amino benzoxazole and 2-chloro or
2-hydroxyacetophenone. Then, these have been used for complexation with CuCl2.2H2O salt to prepare Schiff base metal
complexes via thermal reflux method. Molar conductivity measurement, magnetic moment determination, spectral
techniques including FTIR, 1H NMR and mass spectrometry have been utilized for detailed characterization of the
synthesized compounds. Biological assessment has been carried out employing agar well diffusion process to check the
bio-efficacy of the synthesized compounds against selected microbes, E. coli and B. subtilis (bacteria) and, C. albicans
(fungus). It is concluded from the findings that ligand CO has higher potential amongst all the synthesized compounds.
 
Date 2024-09-24T12:17:04Z
2024-09-24T12:17:04Z
2024-09
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/64588
https://doi.org/10.56042/ijc.v63i9.12304
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJC Vol.63(09) [September 2024]