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<p>Efficacy of <em>Swarna</em><em>-prash </em>in combating perinatal oxidative stress and its compatibility in newborns<span style="white-space: pre;"> </span></p>

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Title Statement <p>Efficacy of <em>Swarna</em><em>-prash </em>in combating perinatal oxidative stress and its compatibility in newborns<span style="white-space: pre;"> </span></p>
 
Added Entry - Uncontrolled Name Singh, Brij Mohan; Banaras Hindu University
Singh, Smriti ; Department of Kaumarbhritya/Balroga, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh 221 005, India
Singh, Kavita ; Department of Kaumarbhritya/Balroga, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh 221 005, India
Tripathi, Yamini Bhushan; Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh 221 005, India
No financial support to this study. The authors acknowledge the contributors
 
Uncontrolled Index Term Microanalysis, Newborns, Oxidative-stress, Swarna-bhasma, Swarna-prash
 
Summary, etc. <p>All neonates are exposed to a variable degree of oxidative stress that may result in cellular, tissue, or organ damage due to a low-efficient antioxidant system. The present study<strong> </strong>aimed to evaluate the effect of licked <em>Swarna-prash</em><em>, </em>comprising 15 mg <em>Swarna-bhasma</em> (incinerated gold particles) mixed with 1 mL honey and 0.5 mL <em>Ghrita</em> (butter oil), given in perinatal oxidative stress. A randomized case-control study ensued after the microanalysis of InAuPs (Incinerated <em>Aurum</em> Particles) and <em>Swarna-prash</em>. Ninety newborns were registered, considering the inclusion and exclusion criteria, and divided into three groups.</p> <p>The single dose of<em> Swarna-prash </em>was given once a day in Group A and thrice a day in Group B. Due to ethical issues, nothing was given except mother milk in Group - C (control group). Venous blood samples were collected from the umbilical cord after birth and 48 h for complete blood counts (CBC), Liver function test (LFT), Renal function tests (RFT), and antioxidant enzymes.</p> <p>The <em>Swarna-bhasma</em> consisted of crystallite-size InAuPs ranging from 30.86 to 114.02 nm. The intergroup analysis of CBC, LFT, RFT, SOD, GSH, and catalase values shows in significant (p&gt;0.05) variation except for the serum bilirubin and SOD in group-B v/s C, offers significant mean values (p&lt;0.05). Finally, it can be inferred that <em>Swarna-prash </em>opposes neonatal perinatal oxidative stress, seems nontoxic, reduces the incidence of physiological jaundice, and is bio-compatible.</p><p> </p>
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2024-10-22 12:30:21
 
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http://op.niscair.res.in/index.php/IJTK/article/view/63527
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 23, ##issue.no## 10 (2024): Indian Journal of Traditional Knowledge
 
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