<p>Design and development of a poly- herbal spray formulation and its physicochemical and biological profiling: from classic to modern drug delivery system</p> <p><strong> </strong></p>
Online Publishing @ NISCAIR
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Title Statement |
<p>Design and development of a poly- herbal spray formulation and its physicochemical and biological profiling: from classic to modern drug delivery system</p> <p><strong> </strong></p> |
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Added Entry - Uncontrolled Name |
Pandey, Shruti ; Banaras Hindu University Mishra, Shardendu ; Department of Pharmacology, Institute of Pharmacy, Ram-Eesh Institute of Vocational and Technical Education, Greater Noida 201 310, India Mishra, Brahmeshwar ; Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology Banaras Hindu University, Varanasi 221 005, Uttar Pradesh, India Chaudhary, Anand Kumar ; Department of Rasa Shastra and Bhaisjya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, Uttar Pradesh, India nil |
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Uncontrolled Index Term |
In vitro drug release, Kinetic model, Mechanical spray, Permeation enhancer, Rasna saptak kwath |
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Summary, etc. |
<p>Many of the polyherbal formulations are described in ayurvedic classics for inflammation and pains. Among them rasna saptak kwath gives best therapeutic effect in clinical studies but palatable issue makes it less popular among patients. The present work emphasizes on the transformation of this classical formulation into more convenient and acceptable form for the patients without disturbing its efficacy. In the present study kwath was converted into mechanical spray form for pain and inflammation. The extractions of herbs were done by both classical and modern methods. The mechanical spray solution was prepared with permeation enhancer, humectant, in suitable solvent system. The spray was standardized on various parameters like viscosity, evaporation time, and spray pattern. Spray was also evaluated for <em>in vitro</em> drug release, anti inflammatory, analgesic and skin irritation study. In the result, the spray pattern was found uniform<strong> </strong>and evaporation time was 9.81±0.30 min. The fluxes for spray were found to be 2.82±.0.11 (µg/cm<sup>2</sup>/h). The kinetic model for spray best fitted to zero order permeation at a constant flux for spray r>0.98. The spray also provides good results in pain and inflammation. So, here is the possibility of replacing that sticky oil of <em>Ayurveda</em> with spray for good relief. The products show the path for a new generation of <em>Ayurvedic dosage</em> form, which has the bright future in this busy schedule of life where integrity of <em>Ayurvedic medicines</em> not hampered.</p><p> </p> |
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Publication, Distribution, Etc. |
Indian Journal of Traditional Knowledge (IJTK) 2024-10-22 12:30:21 |
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Electronic Location and Access |
application/pdf http://op.niscair.res.in/index.php/IJTK/article/view/61136 |
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Data Source Entry |
Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 23, ##issue.no## 10 (2024): Indian Journal of Traditional Knowledge |
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Language Note |
en |
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Nonspecific Relationship Entry |
http://op.niscair.res.in/index.php/IJTK/article/download/61136/465600537 http://op.niscair.res.in/index.php/IJTK/article/download/61136/465600538 |
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