Record Details

Deciphering the Nematostatic Biomolecules from Bacillus cereus against Potential Protein Targets of Rice Root-knot Nematode, Meloidogyne graminicola through Molecular Docking Approaches

Indian Agricultural Research Journals

View Archive Info
 
 
Field Value
 
Title Deciphering the Nematostatic Biomolecules from Bacillus cereus against Potential Protein Targets of Rice Root-knot Nematode, Meloidogyne graminicola through Molecular Docking Approaches
 
Creator ARUNACHALAM, ARUN
ANNAIYAN, SHANTHI
MUTHURAJAN, RAVEENDRAN
BOSE, SEENIVASAN NAGACHANDRA
RAMAMOORTHY, PUSHPAM
GANESAN, SANDEEP
 
Subject Bacterial isolates, in-silico analysis, ligand molecules, picoxystrobin, plant parasitic nematodes
 
Description Rice root-knot nematode Meloidogyne graminicola is a destructive plant parasitic nematode that significantly affects rice production worldwide. Endophytic bacteria confer resistance against nematodes through the production of various bioactive molecules. In the present study, the bioactive molecules produced by Bacillus cereus were evaluated against the potential protein targets of M.graminicola, such as Metalloendopeptidase, MgGPP, MgM0237, MgPDI1, MgPDI2, MgPEL1 and Mg-vap1 (venom allergenlike protein) by employing molecular docking techniques. The study revealed that all the bioactive molecules had a significant impact on the protein targets of M. graminicola. Among the 12 biomolecules, Picoxystrobin and 3-Deoxy-d-mannonic acid had a dominant effect on various protein targets through molecular docking approaches, and these biomolecules from B. cereus can be explored as the novel nematostatic molecules against M. graminicola.
 
Publisher Nematological Society of India
 
Date 2024-09-08
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Identifier https://epubs.icar.org.in/index.php/IJN/article/view/156139
 
Source Indian Journal of Nematology; Vol. 53 No. 2 (2023): Indian Journal of Nematology; 117-130
0974-4444
0303-6960
 
Rights Copyright (c) 2024 Indian Journal of Nematology
https://creativecommons.org/licenses/by-nc-sa/4.0