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Efficacy of Swarna-prash in combating perinatal oxidative stress and its compatibility in newborns

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Title Efficacy of Swarna-prash in combating perinatal oxidative stress and its compatibility in newborns
 
Creator Singh, Smriti
Singh, Kavita
Singh, Brij Mohan
Tripathi, Yamini Bhushan
 
Subject Microanalysis
Newborns
Oxidative-stress
Swarna-bhasma
Swarna-prash
 
Description 958-969
All neonates are exposed to a variable degree of oxidative stress that may result in cellular, tissue, or organ damage due
to a low-efficient antioxidant system. The present study aimed to evaluate the effect of licked Swarna-prash, comprising 15
mg Swarna-bhasma (incinerated gold particles) mixed with 1 mL honey and 0.5 mL Ghrita (butter oil), given in perinatal
oxidative stress. A randomized case-control study ensued after the microanalysis of InAuPs (Incinerated Aurum Particles)
and Swarna-prash. Ninety newborns were registered, considering the inclusion and exclusion criteria, and divided into three
groups.
The single dose of Swarna-prash was given once a day in Group A and thrice a day in Group B. Due to ethical issues,
nothing was given except mother milk in Group - C (control group). Venous blood samples were collected from the
umbilical cord after birth and 48 h for complete blood counts (CBC), Liver function test (LFT), Renal function tests (RFT),
and antioxidant enzymes.
The Swarna-bhasma consisted of crystallite-size InAuPs ranging from 30.86 to 114.02 nm. The intergroup analysis of
CBC, LFT, RFT, SOD, GSH, and catalase values shows in significant (p>0.05) variation except for the serum bilirubin and
SOD in group-B v/s C, offers significant mean values (p
 
Date 2024-10-30T05:46:39Z
2024-10-30T05:46:39Z
2024-10
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscpr.res.in/handle/123456789/64764
https://doi.org/10.56042/ijtk.v23i10.14480
 
Language en
 
Relation Int Cl.24: A61K 36/00
 
Publisher NIScPR-CSIR,India
 
Source IJTK Vol.23(10) [October 2024]