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http://krishi.icar.gov.in/jspui/handle/123456789/1018
Title: | Sequence motif comparison and homology modeling of helper component proteinase (HC–Pro) of banana bract mosaic virus. |
Other Titles: | Not Available |
Authors: | Anuradha, C., Balasubramanian, V. and Selvarajan, R. |
Published/ Complete Date: | 2015-06-10 |
Project Code: | Not Available |
Keywords: | Potyvirus, helper component proteinase, Banana bract mosaic virus, motifs, homology modelling |
Publisher: | Plant Pathology Journal |
Citation: | 1 |
Series/Report no.: | Not Available; |
Abstract/Description: | The Helper Component Proteinase (HC-Pro) is a key protein encoded by the plant viruses of the genus potyvirus. The HC-Pro is involved in different steps of the viral cycle, aphid transmission, replication virus cell-to-cell and systemic movement and is a suppressor of post-transcriptional gene silencing. The amino acid sequence of Banana bract mosaic virus (BBrMV) HC-Pro was compared both inter and intra species across different potyviruses to demonstrate the functional correlation of sequence motifs of HC-Pro to predict its role in virus cycles. Knowledge on the structure of HC-Pro will greatly contribute to understand its multifaceted functions and how structural domains are organized to fulfill them in concert or independently hence, a stable model of BBrMV HC-Pro has been proposed based on homology modeling. The results obtained from this study will provide a framework for new hypothesis and research directions in the area of differential role of HC-Pro. |
Description: | Banana bract mosaic virus (BBrMV), a member of the genus potyvirus, family Potyviridae, has a single stranded positive sense RNA of about 9.7 kb in length (Balasubramanian and Selvarajan, 2012). Banana bract mosaic virus (BBrMV) encodes a single polypeptide that is processed by three viral proteinases to release all viral proteins needed for the infection. |
ISSN: | 1812-5387 |
Type(s) of content: | Research Paper |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Plant Pathology Journal |
NAAS Rating: | 7.57 |
Volume No.: | 14 (3) |
Page Number: | 8 |
Name of the Division/Regional Station: | Crop Protection |
Source, DOI or any other URL: | http://docsdrive.com/pdfs/ansinet/ppj/2015/123-129.pdf |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/1018 |
Appears in Collections: | HS-NRCB-Publication |
Files in This Item:
File | Description | Size | Format | |
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123-129.pdf | 1.1 MB | Adobe PDF | View/Open |
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