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http://krishi.icar.gov.in/jspui/handle/123456789/12770| Title: | Differential expression of Toll-like receptor mRNA in White Leghorn and indigenous chicken of India |
| Other Titles: | Not Available |
| Authors: | Kannaki T Ramasamy, Maddula R Reddy, Dhanutha N Raveendranathan, Shanmugam Murugesan, Rudra N Chatterjee, Rajkumar Ullengala, Santosh Haunshi |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | Directorate of Poultry Research |
| Published/ Complete Date: | 2010-10-01 |
| Project Code: | Not Available |
| Keywords: | Toll like receptors |
| Publisher: | Springer Netherlands |
| Citation: | 17 |
| Series/Report no.: | Not Available; |
| Abstract/Description: | In the present experiment, the expression profile of Toll-like receptor mRNA in indigenous and pure line chickens was studied. The expression of TLR3, TLR4, TLR5 and TLR7 were quantified in heterophils of Aseel, Kadaknath, Naked neck, Dwarf and White Leghorn lines by Quantitative Real-time PCR. White Leghorns expressed significantly (P < 0.01) higher levels of TLR3 mRNA compared to other lines. TLR4 and TLR5 mRNA were significantly highly expressed in Kadaknath line. Among the TLRs investigated TLR5 was more expressed in all lines studied. TLR7 was highly expressed in indigenous chicken Aseel and Kadaknath than other lines. Dwarf chicken expressed significantly (P < 0.01) lower levels of all TLRs investigated. On the basis of the present study we conclude that the differential expression of TLR mRNA in the heterophils of indigenous and other chicken breeds might contribute to their variable disease resistance/susceptibility. |
| Description: | Not Available |
| ISSN: | Not Available |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Veterinary Research Communications |
| NAAS Rating: | 7.29 |
| Volume No.: | 34 |
| Page Number: | 633-639 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | Not Available |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/12770 |
| Appears in Collections: | AS-DPR-Publication |
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