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http://krishi.icar.gov.in/jspui/handle/123456789/13198| Title: | Effect of stearic acid on ovine granulosa cell growth, hormone production, apoptosis, DNA and protein content of oocytes |
| Other Titles: | Not Available |
| Authors: | Farman M Tripathi SK Nandi S Girish Kumar V Gupta PSP Mondal S |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR-NIANP and others |
| Published/ Complete Date: | 2018-01-01 |
| Project Code: | Not Available |
| Keywords: | Oocyte Granulosa cells Stearic acid Apoptosis DNA Protein |
| Publisher: | SOCIETY OF ANIMAL PHYSIOLOGISTS OF INDIA |
| Citation: | Farman M, Tripathi SK, Nandi S, Girish Kumar V, Gupta PSP and Mondal S. 2018. Effect of stearic acid on ovine granulosa cell growth, hormone production, apoptosis, DNA and protein content of oocytes. Indian Journal of Animal Physiology, 5:32-36. |
| Series/Report no.: | Not Available; |
| Abstract/Description: | The present study was undertaken to study the effect of stearic acid (SA), a nonesterified fatty acid (NEFA) on ovine granulosa cell growth, hormone production, apoptosis, DNA and protein content of oocytes. The oocytes and granulosa cells were collected from slaughter house derived ovaries and the cells were exposed to different concentrations of stearic acid to evaluate the granulosa cell growth, estrogen and progesterone production and incidence of apoptosis and some biochemical parameters (DNA and protein content) of oocytes. The cell number increment, monolayer formation rate, apoptosis, estrogen and progesterone production were significantly decreased in stearic acid group. Similarly, Protein and DNA contents of oocyte matured in 30µM stearic acid was significantly decreased compared to control group. In conclusion the metabolic stressors like stearic acid impaired the reproductive functions by impairing the functions of granulosa cell and oocytes in ewes. Key words: |
| Description: | Not Available |
| ISSN: | Not Available |
| Type(s) of content: | Research Paper |
| Sponsors: | Department of Biotechnology, Government |
| Language: | English |
| Name of Journal: | Indian Journal of Animal Physiology |
| Volume No.: | 5 |
| Page Number: | 32-36 |
| Name of the Division/Regional Station: | A.P. DIV |
| Source, DOI or any other URL: | http://www.sapi.in/main/pdf/Indian%20Journal%20of%20Animal%20Physiology.pdf |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/13198 |
| Appears in Collections: | AS-NIANP-Publication |
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