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http://krishi.icar.gov.in/jspui/handle/123456789/13618| Title: | Characterization of leptin gene and analysis of genetic polymorphism in mithun |
| Other Titles: | Not Available |
| Authors: | Not Available ANUPAMA MUKHERJEE SABYASACHI MUKHERJEE NIHAR RANJAN SAHOO IMSUSOSANG LONGKUMER MOONMOON MECH CHANDAN RAJAKHOWA |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::National Research Centre on Mithun |
| Published/ Complete Date: | 2013-08 |
| Project Code: | Not Available |
| Keywords: | Gene, Leptin (obese), Mithun, Sequencing, Polymorphism |
| Publisher: | Indian Journal of Animal Sciences 83 (8): 851–853, August 2013/Short communication |
| Citation: | Not Available |
| Series/Report no.: | Not Available; |
| Abstract/Description: | The present study was designed to characterize leptin gene and to search polymorphism in this gene of mithun. This is the first report on the identification of polymorphism in the leptin gene of mithun. The leptin gene was found to be polymorphic with respect to the locus studied in a sample size of 126 animals. The BB genotype was highly prevalent in the population with a allelic frequency of 0.8 of B allele. The comparison of nucleotide sequence revealed high similarity (98.9%) with Bos indicus and Bos taurus followed by Bos grunniens, Bubalus bubalis, Capra hircus and Ovis aries. Phylogenetic tree revealed that the Bos taurus and Bos indicus formed a cluster with a closer similarity to mithun followed by Bos grunniens, Bubalus bubalis, Capra hircus and Ovis aries respectively. The comparison of DNA sequences of 522 bp leptin gene fragment of mithun with other bovine species revealed 4 mutations, viz. 446 (A/G), 485 (C/T), 497 (C/T) and 512 (A/C) which differentiate this fragment from that of related large ruminants like Bos grunniens, Bos taurus and Bos indicus. |
| Description: | Not Available |
| ISSN: | Not Available |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Indian Journal of Animal Sciences |
| NAAS Rating: | 6.28 |
| Volume No.: | 83 (8) |
| Page Number: | 851–853 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | Not Available |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/13618 |
| Appears in Collections: | AS-NRCM-Publication |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Characterization of leptin gene and analysis of genetic polymorphism in mithun.pdf | 137.06 kB | Adobe PDF | View/Open |
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