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Please use this identifier to cite or link to this item:
http://krishi.icar.gov.in/jspui/handle/123456789/23505
Title: | Camptothecin and 9-methoxy camptothecin, anti-cancer alkaloids in Nothapodytes nimmoniana from Western Ghats, India |
Other Titles: | Not Available |
Authors: | P. KAVITHA, T. VASANTHA KUMAR, P. E. RAJASEKHARAN, V. K. ABDUL KAREEM AND V. K. RAO* |
ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
Author's Affiliated institute: | ICAR::Indian Institute of Horticultural Research |
Published/ Complete Date: | 2010-02-21 |
Project Code: | Not Available |
Keywords: | Camptothecin, 9-methoxy camptothecin, Nothapodytes nimmoniana, monoterpene alkaloid, high performance liquid chromatography |
Publisher: | Not Available |
Citation: | Not Available |
Series/Report no.: | Not Available; |
Abstract/Description: | Nothapodytes nimmoniana is a well known natural source of Camptothecin (CPT), a monoterpene indole alkaloid which exhibits antitumor activity. Its analogs are potent antiviral, anti-HIV agents and chemosterilants. Fortyeight individual trees of N. nimmoniana were chemically profiled from five places of Western Ghats of Karnataka state. There was significant variation in both CPT and 9-methoxy CPT (9-MCPT) contents in stem bark and root bark samples. The present study reveals that in the correlation analysis between CPT and 9- MCPT, there is a linear relationship between accumulation of CPT and 9-MCPT in stem, stem bark and root bark but not in leaves. |
Description: | Not Available |
ISSN: | Not Available |
Type(s) of content: | Research Paper |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Journal of Medicinal and Aromatic Plant Sciences |
NAAS Rating: | Not Available |
Volume No.: | 32 (2) |
Page Number: | 129 |
Name of the Division/Regional Station: | Division of Plant Physiology and Biochemistry |
Source, DOI or any other URL: | Not Available |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/23505 |
Appears in Collections: | HS-IIHR-Publication |
Files in This Item:
File | Description | Size | Format | |
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Camptothecin paper (JAMAPS).pdf | 284 kB | Adobe PDF | View/Open |
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