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Title: | Cloning and sequence analysis of b-tubulin gene of Trypanosoma evansi isolates from Indian dromedaries (Camelus dromedarius). |
Other Titles: | Not Available |
Authors: | M. Ashraf Meera Srivastava S.K. Ghorui G. Nagarajan Shelesh kumar Swami Sanjay Kumar. |
ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
Author's Affiliated institute: | ICAR::National Research Centre on Camel |
Published/ Complete Date: | 2015-01-01 |
Project Code: | Not Available |
Keywords: | ß tubulin gene Dromedarian camel Phylogenetic analysis T. evansi |
Publisher: | Not Available |
Citation: | Not Available |
Series/Report no.: | Not Available; |
Abstract/Description: | Trypanosomosis caused by Trypanosoma evansi is a disease of economic significance of domestic livestock, causing trypanosomiasis, commonly known as Surra. In the present study, gene of Trypanosoma evansi have beer cloned and sequenced. Beta-tubulin is important for cellular structure and physical functions. Sequence analysis of this gene will be useful for the vaccine studies. The open reading frame of b-tubulin of Trypanosoma evansi is 1329 bp in length, encoding 442 amino acid polypeptide. The sequence analysis revealed that the ß tubulin gene of Trypanosoma evansi from India was having the identity of 99% with T.equiperdum, T.evansi (China isolate), T.evansi (Indian isolates), T.brucei and 88% with T.cruzi. The stable biological characteristics of Trypanosomatidae beta-tubulin make it an ideal target of many anti-parasitic drugs that block tubulin function. |
Description: | Not Available |
ISSN: | 0367-6722 |
Type(s) of content: | Article |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Indian Journal of Animal Research |
NAAS Rating: | 6.4 |
Volume No.: | 49(5) |
Page Number: | 618-622 |
Name of the Division/Regional Station: | Not Available |
Source, DOI or any other URL: | 10.18805/ijar.5573 |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/33792 |
Appears in Collections: | AS-NRCC-Publication |
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