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http://krishi.icar.gov.in/jspui/handle/123456789/50949
Title: | SEQUENCE ANALYSIS OF HIGH GLYCINE-TYROSINE KERATIN-ASSOCIATED PROTEINS (KAPs) IN MAGRA SHEEP |
Other Titles: | Not Available |
Authors: | A.S. Meena, Rajiv Kumar*, Ashish Chopra , Ajay Kumar and Arun Kumar |
ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
Author's Affiliated institute: | ICAR::Central Sheep and Wool Research Institute |
Published/ Complete Date: | 2020-10-01 |
Project Code: | AGB/1/02/2017-20 |
Keywords: | Glycine, Keratin associated protein, Lustre, Magra, Single nucleotide polymorphism, Tyrosine |
Publisher: | ISSGPU Society, Avikanagar |
Citation: | Not Available |
Series/Report no.: | Not Available; |
Abstract/Description: | Keratin associated proteins (KAPs) are structural components of the wool fibre. The present study was aimed to analyse nucleotide sequence diversity in three high glycine-tyrosine KAPs gene (HGT-KAP) viz. KAP6, KAP7 and KAP8 from Magra sheep known for lustrous wool. This study was conducted to analyse single nucleotide polymorphisms (SNPs) in these three gene sequences. In open reading frame (ORF), SNPs were not located in KAP 6, however in KAP 7, 14 SNPs were located which leads to 5 synonymous and 9 non-synonymous mutations. In KAP 8 gene only one SNP was present in ORF which leads to tyrosine to asparagine amino acid change. In phylogenetic analysis, KAP 6 proteins of Magra sheep were clustered with KAP 6 amino acid sequence of cashmere goats. Most of the SNPs identified were located into 5' and 3' untranslated regions. Since 5' and 3' untranslated regions play crucial roles in post-transcriptional regulation of gene expression, these SNPs might play some role in lustrous phenotype of the wool. |
Description: | Magra Luster Project |
ISSN: | Not Available |
Type(s) of content: | Article |
Sponsors: | ICAR-CSWRI, Avikanagar |
Language: | English |
Name of Journal: | The Indian Journal of Small Ruminants |
Journal Type: | Research Paper |
NAAS Rating: | 5.95 |
Volume No.: | 26(2) |
Page Number: | 178-182 |
Name of the Division/Regional Station: | Animal genetics and Breeding Division and Arid Region Campus |
Source, DOI or any other URL: | DOI: 10.5958/0973-9718.2020.00017.3 |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/50949 |
Appears in Collections: | AS-CSWRI-Publication |
Files in This Item:
File | Description | Size | Format | |
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2020_IJSR_ASM.pdf | 195.99 kB | Adobe PDF | View/Open |
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