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http://krishi.icar.gov.in/jspui/handle/123456789/78033| Title: | Analysis of the matrix protein gene sequence of the Asian lineage of peste-des-petits ruminants vaccine virus |
| Other Titles: | Not Available |
| Authors: | D Muthuchelvan 1, A Sanyal, B P Sreenivasa, P Saravanan, P Dhar, R P Singh, R K Singh, S K Bandyopadhyay |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::Indian Veterinary Research Institute |
| Published/ Complete Date: | 2006-03-10 |
| Project Code: | Not Available |
| Keywords: | Indian peste-des-petits ruminants, open reading frame, African Lineage Vaccine virus, sequence divergence, matrix protein gene sequence |
| Publisher: | ELSEVIER |
| Citation: | Muthuchelvan D, Sanyal A, Sreenivasa BP, Saravanan P, Dhar P, Singh RP, Singh RK, Bandyopadhyay SK. Analysis of the matrix protein gene sequence of the Asian lineage of peste-des-petits ruminants vaccine virus. Vet Microbiol. 2006 Mar 10;113(1-2):83-7. doi: 10.1016/j.vetmic.2005.10.014. Epub 2005 Nov 16. PMID: 16297575. |
| Series/Report no.: | Not Available; |
| Abstract/Description: | The M gene nucleotide sequence of an Indian peste-des-petits ruminants (PPRV) vaccine virus ("PPRV Sungri/96") belonging to Asian lineage was determined. The gene is 1476 nucleotides long with a single open reading frame (ORF). The nucleotide and predicted amino acid sequence was compared with the homologous region of the African Lineage Vaccine virus "PPRV/Nigeria/75/1". The nucleotide sequence of the "PPRV Sungri/96" was 86% identical to that of "PPRV/Nigeria/75/1", while a homology of 93% and 95% could be observed in the ORF and amino acids level, respectively. The M gene encodes a protein of 335 amino acids, with a predicted molecular weight (MW) of 37.8 kDa. The ORF is flanked by a 3' untranslated region of 436 nucleotides and a high level of sequence divergence (approximately 30%) could be observed in this region between the vaccine viruses of Asian and African lineages. A high degree of conservation of several amino acids of this protein observed previously was also confirmed in this study. |
| Description: | Not Available |
| ISSN: | Not Available |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Veterinary Microbiology |
| Journal Type: | NAAS Journal |
| NAAS Rating: | 9.03 |
| Impact Factor: | 9.03 |
| Volume No.: | 113(1-2) |
| Page Number: | 83-87 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | 10.1016/j.vetmic.2005.10.014 |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/78033 |
| Appears in Collections: | AS-IVRI-Publication |
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