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Title: | Biochemical characterization of liver oil of echinorhinus brucus (bramble shark) and its cytotoxic effect on neuroblastoma cell lines (SHSY-5Y) |
Other Titles: | Not Available |
Authors: | Vishnu, K.V. Ajeeshkumar, K.K. Chatterjee, N.S. Suvanish Kumar Shyni, K. Jayarani, R. Suseela Mathew |
ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
Author's Affiliated institute: | ICAR::Central Institute of Fisheries Technology National Institute of Technology (NIT), Calicut |
Published/ Complete Date: | 2016-05-31 |
Project Code: | Not Available |
Keywords: | Not available |
Publisher: | Hindawi Publishing Corporation |
Citation: | Vishnu, K.V., Ajeeshkumar, K.K., Chatterjee, N.S., Suvanishkumar, Shyni, K., Jayarani, R. and Suseela Mathew (2016) - Biochemical characterization of liver oil of Echinorhinus brucus (Bramble shark) and its cytotoxic effect on neuroblastoma cell lines (SHSY-5Y). Scientifca, Article ID 6294030. |
Series/Report no.: | Not Available; |
Abstract/Description: | The objective of the present study was to characterize the liver oil extracted from the deep sea shark, Echinorhinus brucus, caught from Central Indian Ocean and to evaluate its cytotoxic effect on neuroblastoma cell line (SHSY-5Y). Characterization of liver oil of Echinorhinus brucus revealed the presence of palmitic acid (15%), oleic acid (12%), stearic acid (8%), docosahexaenoic acid (DHA) (18%), and eicosapentaenoic acid (EPA) (16%). It was also found to be a good source of squalene (38.5%) and fat soluble vitamins such as A, D, and K (vitamin A: 17.08mg/100 g of oil, vitamin D: 15.04mg/100 g oil, and vitamin K: 11.45mg/100 g oil). Since it was found to be rich in essential fatty acids, fat soluble vitamins, and squalene, it can be considered as better dietary supplement.The oil of Echinorhinus brucus also showed high in vitro cytotoxic effect against the human neuroblastoma cell line (SHSY-5Y) and the IC50 value laid between 35 and 45 ng. |
Description: | Not Available |
ISSN: | Not Available |
Type(s) of content: | Research Paper |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Scientifica |
Volume No.: | Not Available |
Page Number: | Not Available |
Name of the Division/Regional Station: | Not Available |
Source, DOI or any other URL: | http://dx.doi.org/10.1155/2016/6294030 |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/14233 |
Appears in Collections: | FS-CIFT-Publication |
Files in This Item:
File | Description | Size | Format | |
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Biochemical Characterization of Liver Oil.pdf | 745.68 kB | Adobe PDF | View/Open |
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