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http://krishi.icar.gov.in/jspui/handle/123456789/2733| Title: | Anti diabetic and anti hyperlipidemic activities of different extract of Ailanthus malabarica stem bark in Alloxan-induced diabetic rats |
| Other Titles: | Not Available |
| Authors: | Therasilin Louis Yuvaraj. P Madhavachandran. V Anandan. R |
| Published/ Complete Date: | 2015-01-01 |
| Project Code: | Not Available |
| Keywords: | Antidiabetic Antihyperlipidimic Ailanthus malabarica Stem bark |
| Publisher: | Pharma Intelligence |
| Citation: | International Journal of Biological & Pharmaceutical Research, 6 ( 5 ): 327 - 331, 201 5 |
| Series/Report no.: | Not Available; |
| Abstract/Description: | To evaluate the anti diabetic and anti hyperlipidemic activities of different extracts of Ailanthus malabarica stem bark in alloxan induced diabetic rats. Different extracts (hexane, ethanol and water, 50 mg/kg) of A. malabarica stem bark were administered to alloxan-induced diabetic rats for 21 days and blood glucose levels of the diabetic rats were monitored at one week intervals. Lipid profiles of the treated diabetic rats were determined after the period of treatment. Treatment of alloxan-induced diabetic rats with ethanol extract of A. malabarica stem bark caused a significant (P<0.05) reduction in fasting blood glucose levels of the diabetic rats in 21 days treatment. The ethanol extract showed a comparable action with the reference drug, glibenclamide. The ethanol extract exerted a significant reduction in the levels of serum total cholesterol, triglycerides, LDL, VLDL and phospholipids, and increase in HDL levels of the diabetic rats. However, water and hexane extract of A. malabarica stem bark did not show any such beneficial effects. . These results suggest that the ethanol extract of A. malabarica stem bark possesses anti diabetic effect on alloxan induced diabetic rats and this justifies its usage in ethno medicine and can be exploited in the management of diabetes. |
| Description: | Not Available |
| ISSN: | 2229 - 7480 |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | International Journal of Biological & Pharmaceutical Research |
| Volume No.: | 6(5) |
| Page Number: | 327-331 |
| Name of the Division/Regional Station: | Biochemistry & Nutrition |
| Source, DOI or any other URL: | http://hdl.handle.net/123456789/2251 |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/2733 |
| Appears in Collections: | FS-CIFT-Publication |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 61 ANTI DIABETIC AND ANTI HYPERLIPIDEMIC Louis.pdf | 275.07 kB | Adobe PDF | View/Open |
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