Skip navigation
DSpace logo
  • Home
  • Browse
    • SMD
      & Institutes
    • Browse Items by:
    • Published/ Complete Date
    • Author/ PI/CoPI
    • Title
    • Keyword (Publication)
  • Sign on to:
    • My KRISHI
    • Receive email
      updates
    • Edit Profile
ICAR logo

KRISHI

ICAR RESEARCH DATA REPOSITORY FOR KNOWLEDGE MANAGEMENT
(An Institutional Publication and Data Inventory Repository)


  1. KRISHI Publication and Data Inventory Repository
  2. Fisheries A6
  3. ICAR-Central Institute of Fisheries Technology I5
  4. FS-CIFT-Publication
"Not Available": Please do not remove the default option "Not Available" for the fields where metadata information is not available
"1001-01-01": Date not available or not applicable for filling metadata infromation
Please use this identifier to cite or link to this item: http://krishi.icar.gov.in/jspui/handle/123456789/51816
Title: Dietary chitosan supplementation attenuates isoprenaline-induced oxidative stress in rat myocardium
Other Titles: Not Available
Authors: Anandan, R.
Ganesan, B.
Obulesu, T.
Suseela Mathew
Kumar, R.S.
Lakshmanan, P.T.
Zynudheen, A.A.
ICAR Data Use Licennce: http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf
Author's Affiliated institute: ICAR::Central Institute of Fisheries Technology
Published/ Complete Date: 2012-12
Project Code: Not Available
Keywords: Chitosan
Lipid peroxidation
Antioxidant status
Oxidative stress
Cardio-protective activity
Publisher: Elsevier
Citation: Anandan, R., Ganesan, B., Obulesu, T., Suseela Mathew,Kumar, R.S., Lakshmanan, P.T. and Zynudheen, A.A. (2012) Dietary chitosan supplementation attenuates isoprenaline induced oxidative stress in rat myocardium, Intl. J. Biol. Macromolecules, 51: 783-787.
Series/Report no.: Not Available;
Abstract/Description: Despite considerable advances in diagnosis and management over the last three decades, acute myocardial infarction continues to be a major public health problem. It is predicted that ischemic heart diseases will constitute the major disease-burden worldwide in the year 2020. In the present study, an attempt has been made to examine the effects of dietary chitosan supplementation on lipid peroxidation and cardiac antioxidant defense system in isoprenaline- induced myocardial infarction in rats, an animal model of myocardial infarction in man. Dietary chitosan intake significantly attenuated the isoprenaline- induced lipid peroxidation and maintained the level of reduced glutathione at near normal. Its administration demonstrated an antioxidant effect by maintaining the activities of myocardial glutathione dependent antioxidant enzymes (glutathione peroxidase and glutathione - S - transferase) and antiperoxidative enzymes (superoxide dismutase and catalase) at levels comparable to that of controls. The results of the present study indicate that the salubrious effects of dietary supplementation of chitosan is probably related to a counteraction of free radicals and/or to normal maintenance of the activities of free radical enzymes and the level of GSH, which protect myocardial membrane against oxidative damage by decreasing lipid peroxidation.
Description: Not Available
ISSN: 0141-8130
Type(s) of content: Research Paper
Sponsors: Not Available
Language: English
Name of Journal: International Journal of Biological Macromolecules
Journal Type: International Journal
NAAS Rating: 11.16
Impact Factor: 5.16
Volume No.: 51(5)
Page Number: 783-787
Name of the Division/Regional Station: Not Available
Source, DOI or any other URL: https://doi.org/10.1016/j.ijbiomac.2012.07.016
URI: http://krishi.icar.gov.in/jspui/handle/123456789/51816
Appears in Collections:FS-CIFT-Publication

Files in This Item:
There are no files associated with this item.
Show full item record


Items in KRISHI are protected by copyright, with all rights reserved, unless otherwise indicated.

  File Downloads  

ICAR Data Use Licence
Disclaimer
©  2016 All Rights Reserved  • 
Indian Council of Agricultural Research
Krishi Bhavan, Dr. Rajendra Prasad Road, New Delhi-110 001. INDIA

INDEXED BY

KRISHI: Inter Portal Harvester

DOAR
Theme by Logo CINECA Reports

DSpace Software Copyright © 2002-2013  Duraspace - Feedback