Biomodulation of poly (vinyl alcohol)/starch polymers into composite‑based hybridised films: physico‑chemical, structural and biocompatibility characterization

Abstract

The aim of present research work was to bio-modulate Poly (vinyl alcohol)/Starch (PVA/S) polymers and synthesize compositebased PVA/S hybridised films incorporated with ZnO, TiO2 and gelatin protein hydrolysate (GPH) components. The prepared PVA/S based composite hybridised films were characterized for physico-chemical, thermal and structural characterisation using Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), Thermal gravity analysis (TGA), and X-ray diffraction (XRD) analyses. Notably, the incorporation of composites has made certain physico- chemical and structural modifcations but not altered the molecular structure of biopolymer as revealed by FTIR analysis. The gelatinized blends of PVA/S based hybridised composite flms incorporated with ZnO, TiO2 and GPH components have shown better thermal stability and miscibility as revealed by thermal gravity analysis. The biocompatibility was investigated by evaluating viability of L929 fibroblast cell, which had good biocompatibility and was non-toxic in nature. These PVA/S based composite hybridised films could be implemented in therapeutic biomedical research and food industrial applications.